Friday, March 30, 2012

Back Story : Clomid Cycle #1

So, in November 2011, Dr. M gave me a prescription for Clomid to induce ovulation. The dose was 50mg on cycle days (cd) 3 through 7, and we were told to "do the deed" (DTD) on cd 13, 15, and 17.

On December 28, I began what could best be considered as a light flow. It was more than spotting but less than a full blown period. I called Dr. M's office and the nurse I spoke to said that Dr. M likes to see a "constant flow" in order to judge when cd 1 is. "Well," I thought, "it IS constant.... just low in volume," so I decided to make December 28 officially cd 1. On December 30 I took the first Clomid pill. Fortunately, I experienced no side effects from the Clomid other than a warmer than normal body temperature and a tendency to get mild hot flashes. Some women experience more side effects, including mood swings and increased emotions - like an extreme case of PMS. If you've never tried Clomid before, I would not let the possibility of side effects deter you - the drug absolutely works for many women, but you won't know how you react to it unless you try it.

While I was taking the Clomid, I was doing some research. I belong to a message board for those who have been diagnosed with PCOS, and in particular I follow a thread dedicated to those of us who are on Clomid. Some women there said that they found they were ovulating early with the Clomid, and others said they were ovulating late in their cycle. So, I got the bright idea to extend the time period when we should DTD. We were active on cd 9, 11 and 13..... but then the notion of scheduled "relations" got old. Really old. More for Mr. Lost than for me, but still - scheduled "relations" are not fun relations. We've since learned that you need to up the romance factor to make up for the schedule factor.

We refused to feel bad about the fact that we didn't DTD as much as we probably should have, because we weren't even sure if this cycle would really work or mean anything, thanks to that "is this a period or isn't it?" scenario on December 28.

Beginning around day 9 or so, I also began using an ovulation predictor kit (OPK). The version that I used required you to pee on a stick (some versions use strips of paper). I never saw any positive results from this test, so I was convinced that I didn't ovulate. On cd 21 I went for a blood test to check my progesterone levels - this is the only monitoring that Dr. M does in a Clomid cycle. Other gyn's and nearly all RE's will do ultrasounds to check follicles and whatnot, and this is something we will be pursuing in the future. For this first cycle of Clomid, my cd 21 progesterone was around 3.8.

Now, internet research will tell you that for a "normal" cycle, that number should be around 5 if not higher. The production of progesterone is triggered by ovulation - no ovulation, no progesterone gets made. The progesterone is needed in order to ensure that the lining of the uterus is thick enough to support implantation of the fertilized egg. The progesterone level will climb after ovulation, but if no fertilized egg is implanted, the body is given the signal to stop producing progesterone. That sudden decrease in progesterone is what brings about the next period.

So. My number was only 3.8, but Dr. M was confident that I had shown a response to the Clomid and had ovulated. That had me excited, and I did the normal girly things - my personal Pinterest board suddenly had a "Project Baby" category, full of cribs and nursery sets and birth announcements. I was trying very hard to not get my hopes up, but it was hard to not get excited about the possibility of being pregnant.

Dr. M instructed me to take a home pregnancy test (hpt) on cd 28 if AF had not shown up. If it was negative, I was to wait - if AF had not shown up by cd 35, I was to test again. If that test came back negative, I was to call the office for a serum pregnancy test (blood test). I think I must have tested 3, maybe 4, times between cd 28 and cd 34, which is when AF decided to rear her ugly head. This time around, though, there was no mistaking her - she was definitely a full-fledged period.

So, Clomid Cycle #1 was a bust. Our disappointment was slight and very short lived. As I indicated above, we weren't even sure if this cycle would mean anything. We had come to regard it almost as a "trial run," to see how I would react to the Clomid, to see if 50mg was a strong enough dose, etc. So, no bad feelings - we were just ready to take what we learned into the next cycle..... which is where my next post will pick up. See you then!

4 comments:

  1. Hello! I am so happy that I found your blog! I am beginning my PCOS journey and I have been reading your posts. My husband and I have been TTC and I found out last month I have PCOS. I was also given clomid, but I am switching OB/GYN's to one who is more knowledgable on the subject. Haven't been able to begin the clomid because my cycle hasn't begun.

    I have been trying to find a good support group online. You had mentioned a message board. Which one is it? I think it would be beneficial to me to find a good one!

    Thanks! And again, I enjoy reading your blog!

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    1. Hi Heidi! Thanks so much for your comment :)

      Good luck as you proceed to this next phase of your TTC journey! Kudos for sticking up for yourself and finding a more knowledgeable doctor. Not all doctors are up on the current treatment methods, and not all OB/GYN's will go much beyond Clomid without wanting you to consult a specialist - lessons that I have learned myself in my journey. It's info like that - info about the different steps in the journey - that I've found to be so valuable from online groups & resources.

      The forum I participate in is at SoulCysters.com, which is a general resource on PCOS. When you get to their website, you can click on the link that says "Message Board" to find all kinds of support for women who are in (or who have been in) your shoes. When you get to the message board, look for the box labeled "PCOS Treatments and Conditions" and then look for the heading "Misc Medications" within that box. That's where you'll find some threads that are dedicated to Clomid.

      The boards there have been a great way for me to get a "big picture" sense of what might be coming for us if the Clomid doesn't work. It can be scary at times because there is A LOT of info on those boards, but please, please, please keep in mind the #1 rule about internet resources, especially message boards - "Your mileage may vary." Everyone's experience is different, and just because you might see where one woman had a lot of side effects with a particular treatment or another woman didn't have any success with a particular option does NOT mean that the same will be true for you. I know that sounds like common sense, but I've seen women comment on there about being so scared of the side effects, results, etc just because of one single story that they've heard.

      Thanks again for your comment! I hope that you can find some good info on SoulCysters, and if you have any other questions, feel free to drop me a note :)

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  2. I'm also on cycle #2 of clomid. I have PCOS and we've been trying for 2 years. I take mine on days 5-9 and do the progesterone test on day 23. I know that the earlier taking of the clomid is more for getting a period started and the later taking of the clomid is for actual egg production. After my first cycle my nG was 17 and then we took a month off and I did not ovulate at all. During the first cycle I had hot flashes and mood swings, this time i'm just a little emotional and have only woken up a little sweaty once, not the flashes I had before. I'm eating paleo for the chance the whole clean foods will clean up my system and fight some of the PCOS side effects and it really seems to be working. you should follow my blog as well, I'm putting up all my BBT charting and clomid stuff as well.

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    1. Hi there! Finally getting around to answering some comments. The 3rd Clomid cycle has had no hot flashes or night sweats - but I've definitely been more emotional. I didn't really figure that my side effects would change cycle to cycle, when the dosage has stayed the same, but clearly I was wrong. I've done low carb diets in the past and thought that was the only way I could lose weight with PCOS, but I decided to join Weight Watchers in January. I proved myself wrong - I CAN lose weight on Weight Watchers. It requires diligence and sticking with the program, much like any other program or plan. The paleo diet does look interesting - and it is certainly a cleaner, more "whole" way of eating. Good luck to you, with the diet and the conceiving :)

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